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Results for "

Phorbol myristate

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Peptides

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18739
    Phorbol 12-myristate 13-acetate
    240+ Cited Publications

    PMA; TPA; Phorbol myristate acetate

    		 PKC SphK NF-κB Inflammation/Immunology
    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator . Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells .
    <em>Phorbol</em> 12-<em>myristate</em> 13-acetate
  • HY-136427
    KRM-III

    		Nuclear Factor of activated T Cells (NFAT) Inflammation/Immunology
    KRM-III is a potent and orally active T-cell antigen receptor (TCR) inhibitor. KRM-III inhibits TCR- and phorbol myristate acetate/ionomycin-induced activation of nuclear factor of activated T cells (NFAT) and T-cell proliferation with an IC50 of ~5 μM. Anti-inflammatory activity .
    KRM-III
  • HY-N2609
    7,4'-Dihydroxyflavone
    1 Publications Verification

    		 CCR NF-κB Inflammation/Immunology Endocrinology
    7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
    7,4'-Dihydroxyflavone
  • HY-N5051
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside

    		Others Inflammation/Immunology
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside shows inhibitory activity of neutrophil respiratory burst stimulated by PMA(phorbol myristate acetate) .
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside

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